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diff --git a/covid19-links.md b/covid19-links.md index 4ad9f37..8168851 100644 --- a/covid19-links.md +++ b/covid19-links.md @@ -87,6 +87,36 @@ ## Topical or time-specific links: ## +* [Robust T cell immunity in convalescent individuals with + asymptomatic or mild + COVID-19](https://www.biorxiv.org/content/10.1101/2020.06.29.174888v1) + (2020-06-29 preprint). Key finding: “Our collective dataset shows + that SARS-CoV-2 elicits robust memory T cell responses akin to those + observed in the context of successful vaccines, suggesting that + natural exposure or infection may prevent recurrent episodes of + severe COVID-19 also in seronegative individuals.” + +* [Intrafamilial Exposure to SARS-CoV-2 Induces Cellular Immune + Response without + Seroconversion](https://www.medrxiv.org/content/10.1101/2020.06.21.20132449v1) + (2020-06-20 preprint). Conclusion: “Exposure to SARS-CoV-2 can + induce virus-specific T cell responses without seroconversion. T + cell responses may be more sensitive indicators of SARS-Co-V-2 + exposure than antibodies. Our results indicate that epidemiological + data relying only on the detection of SARS-CoV-2 antibodies may lead + to a substantial underestimation of prior exposure to the virus.” + +* [Systemic and mucosal antibody secretion specific to SARS-CoV-2 + during mild versus severe + COVID-19](https://www.biorxiv.org/content/10.1101/2020.05.21.108308v1) + (2020-05-23 preprint). Main conclusion: “Data show that systemic + IgA and IgG production against SARS-CoV-2 develops mainly in severe + COVID-19, with very high IgA levels seen in patients with severe + ARDS, whereas mild disease may be associated with transient serum + titers of SARS-CoV-2-specific antibodies but stimulate mucosal + SARS-CoV-2-specific IgA secretion. The findings suggest four grades + of antibody responses dependent on COVID-19 severity.” + \[Note that around the end of May I stopped maintaining this list. Still adding a few papers later, but it's definitely less complete than it used to be.\] |